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33 Reasons

acetaminophen causes autism

Acetaminophen and Autism

Based on the scientific evidence we now know that many, if not most, cases of autism are a chemically-induced injury which occurs when babies and children with oxidative stress are given acetaminophen (commonly branded Tylenol in the U.S.).​

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To learn more about the 24 reasons, or lines of evidence, that led to this conclusion scroll down, or select the audience that best fits your interests to read about what to do next.

Evidence Overview

33 and Counting

Currently there are 33 lines of peer-reviewed and published reasons (also called lines of evidence) we know autism is a chemically-induced injury from acetaminophen. This will continue to be updated as more evidence is uncovered, peer-reviewed- and published. 

Categorizing the Evidence

Why did we make categories? We want this to be as easy to understand as possible, and with categories we can give you a quick overview before diving in. While this does not reflect the importance of the lines of evidence, it's a great way to easily scan and remember the topics.

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Pharmacological and Toxicological evidence

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Associations with Medical Practice and APAP use

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Laboratory Animal Studies

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Miscellaneous observations

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Associations in place and time

*Correlation doesn’t necessarily prove causation, but correlation is necessary for causation to exist. Multiple correlations with numerous other lines of evidence can be conclusive.

Image by Manuel Schinner

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Copyright © WPLab, Inc. 2025 

WPLab is a not-for-profit company that conducts research and education related to immune system dysfunction in high-income countries. A current focus is the interaction between the immune system and acetaminophen (paracetamol) early in life, and how that interaction affects brain development. For more information on WPLab, please visit www.wplaboratory.org.

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